Brandon McInnis has noteworthy roles including Finral in Black Clover, Yūta Hibiki in SSSS.Gridman, Gen Asagiri in Dr. Stone, Sir Nighteye in My Hero Academia, and Gyutaro in Demon Slayer: Kimetsu no Yaiba.

His other roles include Milo in Sabikui Bisco, Astolfo in The Case Study of Vanitas, Kenshiro Daimon in ODDTAXI, Samon Goku in Nanbaka, Sonosuke Izayoi in Danganronpa 3, Ares in Banished from the Hero’s Party, Mangod (Hitogami) in Mushoku Tensei, Yūichirō Kurono (Uncle Reaper) in Fire Force, Xane in Fire Emblem Heroes, Featherlight in World of Warcraft: Shadowlands, Patrick Phelps in Black Butler, Ganos in Dragon Ball Super, and many more.

He has also voiced Iketeru in Life Lessons with Uramichi-Oniisan, Edward of Westminster in Requiem of the Rose King, Hirano in Sasaki and Miyano, Saku in ACTORS: Song Connection, Selen in Show By Rock!!, Yuta in Stars Align, Kanata in Ensemble Stars!, Shu Bi in Back Arrow, Al Lyon in Appare-Ranman!, Leonardo in The Gymnastics Samurai, Tsubasa (Kashiwagi’s Boyfriend) in Kaguya-sama: Love is War, Dellinger in One Piece, Makoto Teruhashi in The Disastrous Life of Saiki K, Count St. Germain in Code: Realize, and Keita Amano in Gamers.

Additional Video Game roles of Brandon include Frodo Baggins in Lord of the Rings Online, Lucian in Pokémon Masters, and Zhiyi in Genshin Impact.